If you’ve tried multiple antidepressants and still feel stuck—or if depression symptoms feel urgent and overwhelming—SPRAVATO® may be an option worth exploring. reVIBE Mental Health offers structured, supervised SPRAVATO treatment sessions and a plan that supports you before, during, and after each visit.
SPRAVATO® (esketamine) is a prescription nasal spray used for certain adults with depression. It’s administered in a certified healthcare setting and is typically used alongside an overall treatment plan that may include medication management and therapy.
SPRAVATO is approved for:
SPRAVATO may be appropriate if you:
During your evaluation, our team will review your history, current medications, medical considerations, and safety factors to determine whether SPRAVATO is a fit.
SPRAVATO acts on the brain’s glutamate system and affects the NMDA receptor, which is different than how many traditional antidepressants work. Spravato REMS+1
Some patients notice changes sooner than they have with prior treatments, but response varies—and we’ll set expectations clearly based on your situation.
SPRAVATO is not a “pick up at the pharmacy and use at home” medication. Each session is structured for safety and support:
Most patients start with more frequent visits and taper over time based on response and provider guidance (your plan is individualized).
SPRAVATO is available only through a restricted safety program (REMS) and must be given in a certified healthcare setting. Spravato REMS+1
Because of risks that can include sedation, dissociation, and blood pressure increases, patients must be monitored after each dose and are evaluated before leaving.
To help your session go smoothly, plan for:
Following pre-visit instructions from our team, which may include guidance about food and drink and timing of certain nasal medications.
SPRAVATO often works best when it’s part of a broader treatment approach. Depending on your needs, your plan at reVIBE Mental Health may include:
Some people report improvement early, while others need multiple sessions before noticing meaningful change. We track symptoms and adjust your plan based on data—not guesswork.
Some patients experience sedation or a detached/dissociative feeling during the session, which is one reason monitoring is required.
No—plan for a ride home. You’ll be discharged only when clinically stable, and driving is not permitted after dosing.
They are different treatments. SPRAVATO is FDA-approved esketamine nasal spray delivered under REMS requirements in-office. Spravato REMS+1
If you’re ready to explore whether SPRAVATO is right for you, reVIBE Mental Health can help you understand eligibility, timeline, and coverage considerations.
We currently have five locations for your convenience
We accept most insurance plans. Don’t see your insurance listed?